The Best HP Servers: A Guide to Choosing the Right One for Your Needs

Cloudtechtiq February 11, 2025

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As businesses increasingly transition to cloud-based solutions, having the right hardware infrastructure becomes crucial for ensuring performance, scalability, and reliability. Hewlett Packard Enterprise (HPE) has long been at the forefront of providing high-quality servers that cater to various workloads, from simple data processing to complex, mission-critical applications.

In this blog, we will explore the best HP servers for cloud tech, focusing on key models designed to meet the needs of different business environments. Whether you’re a small business, an enterprise-level corporation, or in need of high-performance computing, HPE offers a diverse range of solutions to support your cloud infrastructure.

1. HPE ProLiant DL380 Gen10

Best for: Enterprise Data Centers and Virtualization

The HPE ProLiant DL380 Gen10 is one of HPE’s most popular and versatile servers, widely used in enterprise data centers. Its reputation for delivering consistent performance, reliability, and scalability makes it a go-to solution for businesses that require high uptime and robust capabilities.

Key Features:

Intel Xeon Scalable Processors: Offers flexibility in terms of processor configurations, making it suitable for a wide range of workloads, including virtualization, cloud computing, and data analytics.

Security-First Design: The HPE Silicon Root of Trust ensures hardware security at the firmware level, protecting your infrastructure from cyber threats.

Scalable Storage Options: With support for up to 30.4TB of storage, this server can handle demanding data applications, with multiple NVMe and SAS SSD options available for fast data access.

Remote Management: Equipped with HPE iLO (Integrated Lights-Out), the server offers remote management, reducing the need for on-site IT personnel.

Ideal for businesses with high demands in terms of performance and virtualization, the DL380 Gen10 is a great all-around solution that can scale with your cloud needs.

2. HPE ProLiant DL385 Gen11

Best for: Virtualized and Multi-Workload Environments

The HPE ProLiant DL385 Gen11 is a single-socket server that packs serious power, making it an excellent choice for workloads like virtualization, cloud computing, and database management. Powered by AMD EPYC processors, it offers a robust platform that can handle a variety of tasks.

Key Features:

AMD EPYC Processors: Supports up to 64 cores for impressive multi-threading performance, perfect for running highly parallelized workloads.

Flexible Storage Options: Configurable with both NVMe and SAS SSDs, it can be tailored for high-speed applications that demand quick access to large data sets.

Memory-Intensive: With support for up to 4TB of memory, the DL385 Gen11 is designed for memory-intensive applications such as virtualization and big data processing.

Energy Efficiency: Built with efficiency in mind, it delivers high performance without consuming excessive power, making it ideal for growing cloud infrastructures.

For businesses focused on high-density virtualization or those running memory-heavy applications, the DL385 Gen11 provides an affordable yet powerful solution that can scale according to your needs.

3. HPE ProLiant DL325 Gen11

Best for: Lightweight Virtualization & Software-Defined Storage

The HPE ProLiant DL325 Gen11 is a compact, cost-effective server that excels in lightweight virtualization and software-defined storage. Featuring the AMD EPYC 7003 series processors, it offers excellent processing power and flexibility in a single-socket design.

Key Features:

AMD EPYC 7003 Series: With impressive single-threaded performance and energy-efficient architecture, it’s a solid choice for businesses with growing virtualized workloads.

Compact Design: Ideal for edge environments and small-to-medium-sized businesses (SMBs), the DL325 Gen11 fits into smaller spaces while offering robust capabilities.

NVMe Storage Options: NVMe drives provide fast data access, ensuring quick retrieval of information for workloads like file services, web hosting, and cloud applications.

Affordable Pricing: Its cost-effectiveness makes it perfect for businesses that need a high-performance solution without the significant investment of larger enterprise servers.

If you’re running virtualized workloads or need software-defined storage capabilities, the DL325 Gen11 is an efficient and affordable choice that doesn’t compromise on performance.

4. HPE Synergy

Best for: Composable Infrastructure

The HPE Synergy platform is a next-generation solution for organizations seeking a composable infrastructure—where compute, storage and networking resources are dynamically allocated based on workload requirements. This platform is designed to enable businesses to scale their cloud infrastructure quickly and flexibly.

Key Features:

Composable Infrastructure: Synergy enables businesses to pool resources and allocate them on demand, reducing inefficiencies and improving performance.

Integration with HPE OneView: Simplifies management by providing a unified interface to control all resources, making it easier to manage complex cloud environments.

Flexible Deployment: Can scale from small, edge environments to large cloud ecosystems, offering unmatched flexibility for dynamic workloads.

Support for Both Intel and AMD Processors: Choose between Intel Xeon and AMD EPYC processors depending on your needs for performance and efficiency.

For businesses that require a highly flexible and scalable cloud infrastructure, HPE Synergy enables rapid adaptation to changing requirements, perfect for modern cloud tech environments.

5. HPE BladeSystem

Best for: Data Center and High-Density Computing

The HPE BladeSystem is a modular blade server solution designed for organizations looking to maximize their data center’s space while maintaining high-density computing. It allows businesses to run multiple applications from a compact footprint, reducing the physical space needed for server infrastructure.

Key Features:

High-Density Architecture: Integrates multiple servers within a single chassis, offering more computing power per square foot, ideal for data centers and cloud-based environments.

Modular and Scalable: Can be easily expanded by adding new blades as needed, making it perfect for businesses with fluctuating cloud requirements.

Energy-Efficient: With its compact design, the BladeSystem reduces energy consumption while providing ample processing power.

Integration with HPE OneView: Provides simplified management through a single interface, improving operational efficiency.

If you’re running a high-density computing environment or managing a data center, the HPE BladeSystem offers an optimal solution, combining efficiency and scalability.

6. HPE ProLiant DL380 Gen10

Best for: General-purpose and Scalable Solutions

The HPE ProLiant DL380 Gen10 is one of the most versatile servers in the HPE ProLiant family. Known for its scalability and reliability, it can support a variety of applications from virtualization to cloud computing to enterprise resource planning (ERP) systems.

Key Features:

Intel Xeon Scalable Processors: Offers powerful computing capabilities, ideal for a wide range of workloads, including virtualized environments, cloud applications, and data-heavy tasks.

Security Features: The HPE Silicon Root of Trust and HPE iLO ensure that your hardware is protected against unauthorized access and vulnerabilities.

Flexible Storage Configurations: Supports both SATA and NVMe storage options, providing the flexibility to choose the best storage solution for your cloud infrastructure.

Energy Efficient: Optimized for low power consumption without sacrificing performance.

For businesses that need a server with broad applicability, including everything from general-purpose applications to complex cloud workloads, the DL380 Gen10 remains a top choice.

7. HPE ProLiant Compute DL384 Gen12

Best for: High-Performance Computing and Virtualization

The HPE ProLiant Compute DL384 Gen12 is part of HPE’s next-generation offerings, built for organizations looking for advanced performance, scalability, and virtualization capabilities. It’s especially suited for workloads that require robust computing power and high-density configurations.

Key Features

Intel Xeon Scalable Processors: Supports the latest Intel Xeon processors for high-speed processing, especially in computational-heavy workloads such as virtualization and analytics.

Flexible Storage: Offers various storage options, including NVMe, which ensures fast data access for demanding applications.

Advanced Security: Integrated security features, such as HPE Silicon Root of Trust, offer protection against firmware attacks and unauthorized access.

Excellent Scalability: Designed to scale from a single server to large, complex environments without compromising performance.

If you need a server for virtualization, cloud infrastructure, or high-performance computing, the HPE ProLiant DL384 Gen12 delivers top-tier power and efficiency for various cloud-based applications.

8. HPE ProLiant Compute DL380a Gen12

Best for: Versatile Enterprise Workloads

The HPE ProLiant Compute DL380a Gen12 is a highly versatile server designed for enterprise environments where performance and efficiency are key. It provides excellent scalability and supports many workloads, from traditional applications to cloud services.

Key Features:

Intel Xeon Scalable Processors: Provides strong performance for mission-critical workloads, including cloud apps and large-scale virtualization.

Memory and Storage Options: Offers support for up to 3TB of RAM and a wide array of storage choices, including NVMe for fast I/O.

Flexible Network Connectivity: With multiple networking options, it ensures high-speed connectivity for large data transfers between servers and cloud environments.

Energy Efficient: Designed with energy-saving in mind, it offers reduced energy consumption without compromising performance.

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For businesses that need a highly adaptable server for cloud workloads and virtualization, the DL380a Gen12 provides a scalable solution that can grow with your needs.

Selecting the right server is a fundamental decision that shapes the efficiency and growth of your cloud infrastructure. HPE’s extensive lineup of servers—ranging from powerful ProLiant models to Synergy and BladeSystem solutions, provides businesses with the flexibility and performance needed to tackle today’s diverse workloads. With cutting-edge features like advanced security, robust scalability, and energy-efficient designs, HPE’s offerings are ideal for organizations looking to optimize their cloud computing capabilities. No matter the size of your business or the complexity of your requirements, HPE servers provide reliable, future-proof solutions that can grow alongside your cloud journey, ensuring both innovation and operational excellence.